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Our Research
About the Applied Dynamic Mechanics Laboratory
The Applied Dynamic Mechanics Laboratory at the University of Connecticut investigates how molecular structure, mechanical forces, and interactions among individual components shape biological and autonomous systems. Our research combines experiments, mathematical modeling, computational simulation, and machine learning.
In cellular mechanics, we study how membrane and cytoskeletal organization govern the deformation, adhesion, protein diffusion, and stability of red blood cells and neurons. Atomic force microscopy, force spectroscopy, advanced fluorescence microscopy, and coarse-grained molecular dynamics connect molecular mechanisms to cellular behavior in health, disease, and injury, including sickle cell disease and axonal damage.
Our robotics research develops compact autonomous underwater vehicles (mini-AUVs), integrating computer vision, deep reinforcement learning, and docking systems. Simulations and underwater experiments support navigation, obstacle avoidance, and multi-agent coordination for inspection of submerged hulls, ports, and bridge foundations.
In applied quantum computing, we explore hybrid quantum–classical methods for swarm navigation and investigate how local decisions produce collective behavior. We also investigate quantum reservoir computing for temporal information processing, swarm dynamics, and electroencephalogram (EEG) classification in epilepsy and mild traumatic brain injury.
Across these areas, our goal is to establish predictive models, explain complex behavior, and develop experimentally grounded methods that advance cellular biophysics, intelligent autonomy, and efficient computation.
Research & Lab News
- Differential Control of Small-conductance Calcium-activated Potassium Channel Diffusion by Actin in Different Neuronal Subcompartments May 11, 2023Small-conductance calcium-activated potassium (SK) channels show a ubiquitous distribution on neurons, in both somatodendritic and axonal regions. SK channels are associated with neuronal activity regulating action potential frequency, dendritic excitability, and synaptic plasticity. Although the physiology of SK channels and the mechanisms that control their surface expression levels have been investigated extensively, little is known […]Shiju Gu
- Dynamics of the axon plasma membrane skeleton March 20, 2023It was recently revealed via super-resolution microscopy experiments that the axon plasma membrane skeleton (APMS) comprises a series of periodically arranged azimuthal actin rings connected via longitudinal spectrin filaments forming an orthotropic network. The common perception is that APMS enhances structural stability of the axon but its impact on axon deformation is unknown. To investigate […]Zhaojie Chai
College News
- UConn Researchers Uncover Water’s Critical Role in Human Tissue Elasticity November 9, 2026New research from Anna Tarakanova and Metehan Çam offers insight into a decades-long scientific debate about what makes the human body’s tissues stretch and spring back.Sarah Redmond
- NIH Grant Supports Development of Innovative 3D Organoid Platform for Drug Discovery November 9, 2026Xueju “Sophie” Wang is developing a “micro-lab” to support organoid growth and functional evaluationAnna Zarra Aldrich '20 (CLAS), Office of the Vice President for Research
- Northeast Power Electronics Symposium To Be Held at UConn for the Third Year November 6, 2026The third annual NEPES symposium will be held at UConn this November, bringing together industry leaders, researchers, and students to explore emerging technologies and strengthen collaborations.Sarah Redmond
- Professor Sir Cato T. Laurencin Delivers Keynote Address at the Advanced Therapies in Orthopaedics (ATiO) Foundation Annual Meeting November 2, 2026Laurencin spoke on Regenerative Engineering at the 2026 ATiO Conference in Berlin, Germany.Sara Capozzi
UConn Community News
- Mulch Ado About Plastics: Shuresh Ghimire Works to Make Mulch More Sustainable November 9, 2026“If we increase crop yield, it may help humans in the short term. But if we’re degrading the environment, that would ultimately, in the long term, harm humanity. Everything we do should be in the One Health framework.”
- UConn Expanding Spring Commencement Schedule to Ease Traffic and Parking, Give Guests More Time to Celebrate November 9, 2026'Moving forward, candidates and guests can linger comfortably on campus, perhaps stopping to take photographs at their favorite spots, and not feel so rushed to leave'
- UConn Researcher Takes a Look at Relationship Between Women and Guns November 9, 2026‘When we don’t ask questions about how this is different for women, we then don’t look for policy solutions that will help address the part of this epidemic that women bear’
- UConn Researchers Uncover Water’s Critical Role in Human Tissue Elasticity November 9, 2026New research from Anna Tarakanova and Metehan Çam offers insight into a decades-long scientific debate about what makes the human body’s tissues stretch and spring back.