Discover. Learn. Apply.
Our Research
About the Applied Dynamic Mechanics Laboratory
The Applied Dynamic Mechanics Laboratory at the University of Connecticut investigates how molecular structure, mechanical forces, and interactions among individual components shape biological and autonomous systems. Our research combines experiments, mathematical modeling, computational simulation, and machine learning.
In cellular mechanics, we study how membrane and cytoskeletal organization govern the deformation, adhesion, protein diffusion, and stability of red blood cells and neurons. Atomic force microscopy, force spectroscopy, advanced fluorescence microscopy, and coarse-grained molecular dynamics connect molecular mechanisms to cellular behavior in health, disease, and injury, including sickle cell disease and axonal damage.
Our robotics research develops compact autonomous underwater vehicles (mini-AUVs), integrating computer vision, deep reinforcement learning, and docking systems. Simulations and underwater experiments support navigation, obstacle avoidance, and multi-agent coordination for inspection of submerged hulls, ports, and bridge foundations.
In applied quantum computing, we explore hybrid quantum–classical methods for swarm navigation and investigate how local decisions produce collective behavior. We also investigate quantum reservoir computing for temporal information processing, swarm dynamics, and electroencephalogram (EEG) classification in epilepsy and mild traumatic brain injury.
Across these areas, our goal is to establish predictive models, explain complex behavior, and develop experimentally grounded methods that advance cellular biophysics, intelligent autonomy, and efficient computation.
Research & Lab News
- Differential Control of Small-conductance Calcium-activated Potassium Channel Diffusion by Actin in Different Neuronal Subcompartments May 11, 2023Small-conductance calcium-activated potassium (SK) channels show a ubiquitous distribution on neurons, in both somatodendritic and axonal regions. SK channels are associated with neuronal activity regulating action potential frequency, dendritic excitability, and synaptic plasticity. Although the physiology of SK channels and the mechanisms that control their surface expression levels have been investigated extensively, little is known […]Shiju Gu
- Dynamics of the axon plasma membrane skeleton March 20, 2023It was recently revealed via super-resolution microscopy experiments that the axon plasma membrane skeleton (APMS) comprises a series of periodically arranged azimuthal actin rings connected via longitudinal spectrin filaments forming an orthotropic network. The common perception is that APMS enhances structural stability of the axon but its impact on axon deformation is unknown. To investigate […]Zhaojie Chai
College News
- UConn’s Professor Sir Cato T. Laurencin Receives Leadership and Advocacy Award from InterCommunity Health Care November 9, 2026Laurencin was honored for his commitment to bettering public health through his medical advancements, advocacy, and mentorship.Sara Capozzi
- UConn Researchers Uncover Water’s Critical Role in Human Tissue Elasticity November 9, 2026New research from Anna Tarakanova and Metehan Çam offers insight into a decades-long scientific debate about what makes the human body’s tissues stretch and spring back.Sarah Redmond
- NIH Grant Supports Development of Innovative 3D Organoid Platform for Drug Discovery November 9, 2026Xueju “Sophie” Wang is developing a “micro-lab” to support organoid growth and functional evaluationAnna Zarra Aldrich '20 (CLAS), Office of the Vice President for Research
- Northeast Power Electronics Symposium To Be Held at UConn for the Third Year November 6, 2026The third annual NEPES symposium will be held at UConn this November, bringing together industry leaders, researchers, and students to explore emerging technologies and strengthen collaborations.Sarah Redmond
UConn Community News
- From Storrs to Stonybrook: Alum Explores The Baby-Sitters Club’s Legacy November 10, 2026Daniela Doncel ’19 hosts CT Public's Generation: Baby-Sitters Club, celebrating its 40-year legacy
- NIH Extends UConn Pepper Center Grant November 10, 2026The Center, which specializes in Precision Gerontology, plans interdisciplinary expansion to Storrs
- CAHNR Scholars Celebration Honors Student Achievement and the Power of Donor Support November 10, 2026“A scholarship is an investment in a student today, but its impact can carry forward throughout a career and into the communities that student will one day serve”
- UConn’s Professor Sir Cato T. Laurencin Receives Leadership and Advocacy Award from InterCommunity Health Care November 9, 2026Laurencin was honored for his commitment to bettering public health through his medical advancements, advocacy, and mentorship.